吴双

发布时间:2021-04-21 10:55:17


个人简介

吴双,博士,副研究员。主要从事肿瘤精准靶向治疗研究。主持国家重点研发计划子课题,重庆市自然科学基金面上项目,重庆市留创计划创新类项目等多项课题。

研究领域:

第一,基于磁共振波谱 (MRSI) 技术的分子成像手段监测肿瘤微环境成分的实时变化,从而实现非侵入式活体追踪肿瘤在治疗过程中的演化进程。

第二,探究免疫疗法Immunotherapy在临床前胶质母细胞瘤的治疗中的应用。

第三,研究临床前胶质母细胞瘤在化疗中产生耐药性的原因。

专业方向

药剂学、免疫学、医学影像学

所授课程:

研究生:《生物医学前沿进展》

代表性论文:

1. Cheng L, Ma Z, Yang X... Wu S* & Li, C*. All-stage targeted therapy for invasive cryptococcosis through interaction between the secretory protein Cig1 and hemin[J]. Asian Journal of Pharmaceutical Sciences, 2025, 20(4): 101053. (IF= 10.7)

2. Ma Z, Liu X, Xie X ... Wu S* & Li, C*. Vinpocetine-mediated multidimensional active targeted delivery across the blood-brain barrier[J]. Journal of Controlled Release, 2025, 382: 113768. (IF= 10.5)

3. Wu S, Song R, Liu T, et al. Antifungal therapy: novel drug delivery strategies driven by new targets[J]. Advanced Drug Delivery Reviews, 2023: 114967.(IF = 17.9)

4. Wu S, Calero-Pérez P, Villamañan L, et al. Anti-tumour immune response in GL261 glioblastoma generated by Temozolomide Immune-Enhancing Metronomic Schedule monitored with MRSI-based nosological images. NMR Biomed. 2020;33(4):e4229. (IF 3.5)

5. Wu S, Calero-Pérez P, Arús C, et al. Anti-pd-1 immunotherapy in preclinical gl261 glioblastoma: Influence of therapeutic parameters and non-invasive response biomarker assessment with mrsi-based approaches[J]. International journal of molecular sciences, 2020, 21(22): 8775.(IF = 5.6)

6. Tang Y, Wu S, Lin J, et al. Nanoparticles Targeted against Cryptococcal Pneumonia by Interactions between Chitosan and Its Peptide Ligand. Nano Lett. 2018;18(10):6207–6213. (共同一作IF 12.3)

电话邮箱:

psychews@gmail.com